Supplements

Feeling tired all the time? Memory not what it used to be? Struggling to complete physical tasks that you used to normally take in your stride?

All these are common complaints that can result from a myriad of different medical problems… but there is often just one cause that links them all – vitamin B12 deficiency.

We get B12 from animal products such as meat, fish, milk and eggs. It is one of the water-soluble B vitamins which is bound to protein within food. However, you may be struggling to get enough through a healthy diet as it is notoriously hard to absorb through the gut.

What does vitamin B12 do?

Vitamin B12 helps the body’s ability to reduce the onset of fatigue and increase concentration levels by contributing to a normal energy metabolism.

Vitamin B12 is essential for the formation of red blood cells and the development and normal functioning of the brain and nervous system, particularly those aspects which determine concentration, learning, memory and reasoning.

Sources of vitamin B12

We get B12 from animal products such as:

• Red meat
• Fish
• Milk
• Eggs
• It can also be found in fortified foods

However, you may be struggling to get enough through a healthy diet as it is notoriously hard to absorb through the gut due to its large molecular size.

Who needs vitamin B12?

B12 is a notoriously difficult nutrient to absorb in the gut. At most only 1% of our dietary intake will be absorbed by the body. Diet and life-stages also have an impact on your vitamin B12 requirements, most notably:

Vegetarians and vegans

Who may have restricted B12 intake due to limited diet.

Pregnant and breastfeeding mothers

Not only essential for the mother but vitamin B12 crosses the placenta during pregnancy and is present in breast milk.

Those with malabsorption issues

As we age our secretion of hydrochloric acid in the stomach reduces and we become more vulnerable to depletion.

Athletes

With increased workout intensity the body will develop nutritional imbalances effecting stamina, strength and performance.

Frequent travelers

Can help energy levels when traveling, particularly over long distances where sleep patterns are disrupted.

Pernicious Anemia Sufferers

Can be used between injections to help boost vitamin b12 levels.

Vitamin B12 Deficiency

B12 is a notoriously difficult nutrient to absorb in the gut. At most only 1% of our dietary intake will be absorbed by the body, and that relies on digestive efficiency and the presence of a chemical called intrinsic factor.

Deficiency can occur at any age and in the past, we have associated deficiency with growing older and our inability to extract the large molecule from our diet. However, more and more children and teenagers are being diagnosed with a deficiency. In extreme cases deficiency (known as pernicious anaemia) can cause severe nerve damage.

Our livers hold large stores of B12 and deficiency tends to develop over many years and because symptoms can easily be mistaken, diagnosis is often missed. Symptoms vary but include one or more of the following: fatigue, vague mental fogging and memory problems, depression, weakness, pins and needles in the hands and feet, and an unsteady walk.

The most common causes of vitamin B12 deficiency are:

• An autoimmune condition – pernicious anaemia
• Food-bound vitamin B12 malabsorption
• Restricted diets
• Increasing age

Tiredness, stress, ill-health, poor or limited diet will all reduce this absorption further.

How do I raise my vitamin B12 levels?

A B12 supplement can be the easiest way to raise your B12 levels. As a water-soluble vitamin there is no upper daily limit to how much you can take. However, because of the difficulty in absorbing such a large molecule, tablets and capsules are notoriously difficult for the gut to break down and digest.

A daily B12 oral spray, applied directly onto the inner cheek of the mouth, it avoids over-reliance on our digestive system. Absorption commences immediately. It’s fast, it’s convenient and it tastes great.

Our work with the Pernicious Anaemia Society

There are many people who suffer with Pernicious Anaemia and have insufficient levels of B12. This is not a problem with the blood but rather with the digestive system. Some people do not produce the intrinsic factor which hampers their absorption of B12, however this is a very small percentage of Pernicious Anaemia sufferers. The majority of people do produce the intrinsic factor but for some unknown reason, they also produce something that kills off the intrinsic factor, Anti-Intrinsic Factor Antibodies.

If you have been diagnosed with pernicious anaemia by your doctor he will undoubtedly have prescribed a course of B12 injections. Depending upon you level these will be weekly, monthly or every three months and vary in dosage levels. However, this form of treatment often results in symptoms returning before the next injection is due and this is one vital service BetterYou Boost B12 oral spray delivers.

With thanks to BetterYou for this article about the importance of B12. You can read the original piece here.

This article on the importance of magnesium is written by Marta Anhelush of Biocare.

If there’s one nutrient we should all consider supplementing, it’s magnesium. Magnesium is one of the most important elements in our body, being involved in over 300 enzymatic reactions.^[i] Up to 60% of it is stored in our skeleton. Therefore, just like calcium, it is important for healthy bones and prevention of conditions such as osteoporosis. Its functions stretch far beyond musculoskeletal health, though, and include:

• Protein synthesis
• Muscle and nerve function
• Blood glucose management
• Heart function and blood pressure regulation
• Energy production.^[ii]

In fact, magnesium is so essential to so many biological functions, that getting extra through diet or supplementation would be beneficial to everyone.

Unfortunately, many of us don’t consume enough magnesium-rich foods. In addition, modern lifestyle can create a big drain on our magnesium reserves. Because magnesium is used for so many processes, it can get easily depleted, especially by stress, erratic eating patterns, high sugar diets, or overtraining. Some common medications, such as acid blockers used for reflux, can also reduce absorption of magnesium.

HOW WOULD YOU KNOW IF YOU NEED MORE MAGNESIUM?

If you suffer from headaches, PMS, muscle cramps, high blood pressure, anxiety, constipation, fatigue, memory problems, hyperactivity, you could be deficient. In fact, a study done in America showed that 48% of the population had inadequate intake of this vital mineral.^[iii]

You can naturally increase your magnesium levels by adding more magnesium-rich foods to your diet:

• Vegetables: leafy greens (spinach, kale, chard, broccoli), and squash
• Nuts and seeds like pumpkin, sunflower and sesame seeds, almonds and cashews
• Healthy grains and beans such as quinoa and black beans
• Also try magnesium baths, using Epsom salts or magnesium flakes. They can be great to relieve muscle pain or help you to relax in the evening.

Make sure you integrate lifestyle strategies to reduce magnesium depletion; eat nutritious foods at regular times, avoid processed foods and refined carbohydrates, reduce stress and allow time for your body to recover from exertion. Ensure your digestion is working optimally to enhance magnesium absorption. If you suffer with any digestive complaints, consider using probiotics or digestive enzymes to help.

SUPPLEMENTATION – WHAT’S THE RIGHT TYPE OF MAGNESIUM FOR YOU?

Increasing food sources of magnesium should be a priority but, if your requirements are high, or if you already have symptoms of deficiency, food alone may not be enough. There’s growing evidence that supplementing magnesium, especially specific types, can help with supporting certain aspects of health. You see, not all magnesium is equal. Choosing the right type is critical to successful nutritional support.

Just as with any other mineral, magnesium has to be bound to a ‘carrier’ molecule when it is consumed in a supplement form. The type of this carrier will determine its use and absorption rate, so it is important to choose the one that suits you best. For example, magnesium citrate was shown to be much more bioavailable (better absorbed and used by the body)than magnesium oxide.^[iv] You can also benefit from the other molecule that the magnesium is bound to, as they all have their own unique functions in the body. Some of the most commonly used ones include:

• Magnesium Citrate – a well absorbed, gentle form that delivers a good amount of magnesium per capsule. So it’s a great choice for general magnesium supplementation when you want a higher dose. One particular study successfully used 600mg of magnesium citrate in the prophylaxis of migraines.^[v] It also acts as a gentle laxative so may be helpful to relieve constipation.^[vi] In addition, long-term supplementation of magnesium citrate alongside potassium reduced the risk of recurrent kidney stones by 85%.^[vii]
• Magnesium Glycinate –glycine is an amino acid used for a number of important proteins in the body, including haemoglobin in red blood cells or creatine in the muscle. It supports the nervous system, reducing stress and promoting sleep, and improving memory, attention and learning.^[viii],[ix] Glycine is a pre-cursor to glutathione – our most potent antioxidant and detoxifier,^[x],[xi] and one of the largest components of collagen, which is crucial for healthy skin, joints, ligaments, tendons and bones. Insufficient dietary intake of glycine may interfere with collagen production.[xii]
• Magnesium Malate –malic acid is a natural compound found in many different foods (e.g. apples). In the body, it is important for energy production. It’s been found to reduce tiredness, tenderness, pain and fatigue in fibromyalgia.^[xiii],[xiv]So magnesium malate may be a better choice for those people with energy and fatigue issues. It may also be beneficial for muscle pain and cramps. It doesn’t give quite as much magnesium as other forms, but this isn’t an issue as the malate part is just as important in supporting energy.
• Magnesium Taurate –an amino acid – taurine, is used to create bile which helps with absorption of fats^[xv] in the digestive tract and detoxification of toxins. Through its impact on bile production, it aids natural elimination of cholesterol. In studies, it’s been found to lower LDL cholesterol^[xvi],[xvii] and triglycerides, while increasing HDL cholesterol.^[xviii] It is also used by the heart muscle for contractions, and may improve arterial function, supporting healthy circulation and blood pressure.^[xix],[xx] Taurine also supports the nervous system by activating the calming neurotransmitter GABA.^[xxi] So to summarise, magnesium with taurine can be particularly helpful for people with liver or heart problems, poor gallbladder function and reduced fat digestion^[xxii] or those with high stress levels or insomnia.

Many of us may need additional magnesium support, but it is important to remember that not all magnesium is equal. Choose the best form for your specific needs and if you need any help, you can call our Clinical Nutrition team or see a practitioner for further advice and support.